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Translational Research Center for Integrative Omics

Mingqing XU

Ph. D., Research Professor, Principal Investigator

Email: mingqingxu@gmail.com


        Dr. Xu published 14 first author and corresponding author papers, with a total impact factor of more than 100 and total cites of more than 400. Dr. Xu has won Shanghai Outstanding Doctoral Dissertation Award, nomination of National Excellent  Doctoral Dissertation and Bio-X Award. He now works as associate editor of BMC Psychiatry, BMC Medical Genomics and editoral board member of Progress in Neuro-Psychopharmacology and Biological Psychiatry.



        Epidemiology, genomics and bioinformatics study of complex human diseases. Recently, Dr. Xu's research focuses on intergrating and cross analysis on multi omics data of cardiovascular disease and neuropsychic disease as well as systems biology. Besides, with molecular markers of multi omics data, he intends to conduct disease risk prediction model to better serve for clinic.



1. Xu M*, Sham P, Ye Z, Lindpaintner K, He L. A1166C genetic variation of the angiotensin II type I receptor gene and susceptibility to coronary heart disease: Meta-analysis of 53 studies with 20,435 cases and 23,674 controls. Atherosclerosis. Atherosclerosis. 2010;213(1):191-9.

2. Xu M*, St Clair D, He L. Testing for genetic association between the ZDHHC8 gene locus and susceptibility to schizophrenia: An integrated analysis of multiple datasets. Am J Med Genet B Neuropsychiatr Genet. 2010; 153B(7):1266-75.

3. Xu MQ*, Sun WS, Liu BX, Feng GY, Yu L, Yang L, He G, Sham P, Susser E, St Clair D, He L. Prenatal malnutrition and adult schizophrenia: further evidence from the 1959-1961 Chinese famine. Schizophr Bull. 2009; 35(3):568-576

4. Xu MQ*, Ye Z, Hu FB, He L. Quantitative assessment of the effect of angiotensinogen gene polymorphisms on the risk of coronary heart disease. Circulation 2007; 116(12):1356-66.

5. Xu MQ*, Xing QH, Zheng YL, Li S, Gao JJ, He G, Guo TW, Feng GY, Xu F, He L. Association of AKT1 gene polymorphisms with risk of schizophrenia and with response to antipsychotics in the Chinese population. J Clin Psychiatry. 2007; 68(9):1358–1367.

6. Xu MQ*, St Clair D, Ott J, Feng GY, He L. Brain-derived neurotrophic factor gene C-270T and Val66Met functional polymorphisms and risk of schizophrenia: a moderate-scale population-based study and meta-analysis. Schizophr Res. 2007 Mar;91(1-3):6-13.

7. St Clair D#, Xu M#, Wang P, Yu Y, Fang Y, Zhang F, Zheng X, Gu N, Feng G, Sham P, He L. Rates of adult schizophrenia following prenatal exposure to the Chinese famine of 1959-1961. JAMA. 2005; 294(5):557-62.

# Contributed equally to the paper * Corresponding author

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